Torna alla pagina Eventi 2023 - Seminari BIOMORF
14 aprile 2023, ore 15
Aula "De Simone", piano I, Torre Biologica (Pad. G), A.O.U. "G. Martino" - Microsoft Teams
PRESENTAZIONE DELL'EVENTO
Prof. Sergio Baldari
Direttore Dipartimento BIOMORF, Università di Messina
Prof. Andrea D'Avella
Coordinatore Commissione AQ-RDTM del Dipartimento BIOMORF, Università di Messina
Prof. Gaetano Caramori
Dipartimento BIOMORF, Università di Messina
RELATORI
Prof. Ian Adcock
National Heart and Lung Institute, Imperial College London, UK
"Epigenetic and respiratory diseases"
Epigenetic changes are not correlated with DNA sequence but with reversible post-translational modifications including histone acetylation, methylation and hosphorylation modulating gene expression in different cell types. Impaired epigenetic processes can increase the risk of development of several diseases, including asthma, chronic obstructive pulmonary disease (COPD) and lung cancer. The expression and activity of many enzymes modulating epigenetic changes are impaired in the lower airways of patients with these respiratory diseases.
Prof. Trevor Hansel
National Heart and Lung Institute, Imperial College London, UK
"The impact of Respiratory Syncytial Virus (RSV) infection on lung development in pediatric age"
Respiratory syncytial virus (RSV) is a common infection in newborns particularly when preterm (≤35 weeks' gestation) representing the most important cause of acute bronchiolitis in children worldwide. Many children with previous RSV infection can develop respiratory diseases later in their life, this may be correlated to an impaired lung development induced by the RSV infection through alterations in lung microbiota, neural pathways and lower airways remodelling.